Synechocystis sp. PCC6803 : slr0116

ORF IDslr0116
Gene namepcyA
Definition3Z-phycocyanobilin:ferredoxin oxidoreductase
Position2996695..2997441    
Length248 aa
747 bp   +upstreambp   +downstreambp
CyanoBaseslr0116 phycocyanobilin:ferredoxin oxidoreductase
UniProtQ55891 Phycocyanobilin:ferredoxin oxidoreductase (EC 1.3.7.5).
KOK05371 pcyA; phycocyanobilin:ferredoxin oxidoreductase [EC:1.3.7.5]
Pfam / Prositepf:Fe_bilin_red
Ortholog    
Paralog  

CommentPcyA serially reduces the vinyl group of D-ring and A-ring of biliverdin IXa using electons from ferredoxin to produce phycocyanobilin.
Remark
Mutant
Category
Porphyrin and chlorophyll metabolism
Reference
1. Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC (2001) Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms. Plant Cell 13:965-78. [PMID:11283349]
2. Tooley AJ, Cai YA, Glazer AN (2001) Biosynthesis of a fluorescent cyanobacterial C-phycocyanin holo-alphasubunit in a heterologous host. Proc Natl Acad Sci U S A 98:10560-5 [PMID:11553806]
3. Hagiwara Y, Sugishima M, Takahashi Y, Fukuyama K (2006) Crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IXalpha, a key enzyme in the biosynthesis of phycocyanobilin. Proc Natl Acad Sci U S A 103:27-32. [PMID:16380422]
PubMed search
Homology BLAST     FASTA
3D Structure PDB     GTOP
Fluorome



[ CYORF | GenomeNet ]